The late- Mr. John W. Nick died from breast cancer June 11,  1991, at the age of 58.                            

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John's Tissue Report:




John W. Nick Breast Cancer Tissue Report from St. Francis Hospital Roslyn, New York. Pathologist D. Mahapatro, M. D. Anagostopoulos,M.D.


July 13-1989 Age 56 years old Attending Physician Dr. Rogers

CliPathnical Diagnosis Right Breast

Microscopic Examination: Pathology Report Male Breast Cancer.


A. Right Breast:
Received fresh is a right breast measuring 12x6x5 cm. An ellipse of skin is partially covering the breast measuring 11x7cm. The nipple is centrally located and appears subtracted. One serial sectioning of the breast, the nipple. The tumor appears to infiltrate the dermis and estenals 1 cm. from the deep resection line. Part of the tumor has been frozen. Frozen Section Diagnosis: Infiltrating Duct Cell Carconama involving the dermis.

 Submitted by DR. Agnagnostopoulos. Tissue fro estrogen and progestarone receptors has been taken and representative sections have been submitted.


 B. Lymph Node Masses from Levels One and Two:
 Received in formalin is a mass measuring 6 cm. in greatest dimension. On sectioning, matted lymph nodes replaced by tumor are seen. The tumor mass measures 4 cm. in greatest dimensions. The tissue for estrogen and progesterone receptors has been taken and representative sections have been submitted.

Microscopic Examination: Male Breast Cancer, "Pagent's Disease." Which is an inverted nipple accompanied by local pain or itching.


Multiple sections reveal infiltrating duct cell carcinoma of breast. The tumor is composed of multiple small and large aggregates of round cuboidal cells, at places forming ducts. In the center of the tumor, extensive necrosis and sclerosis are noted. The tumor infiltrates into the dermis and also into the nipple and areola. Focally, the tumor cells are also present in the epidermis where ulceration is noted. Pervascular lymphatic invasion is identified. The section from axillary lymph nodes and matted gropps of axillary lymph nodes show extensive replacement by metastatic duct carcinoma. The tumor also infiltrates into fibroadipose tissue around the lymph nodes from axilla. The skin margin and posterior margin of resection of breast are free of pathological changes.

Pathological Diagnosis:

 Infiltrating Duct Carcinoma of Breast involving the nipple, areola and adjacent skin associated with Microscopic Pagent's Disease, clinically right (2.5 cm in diameter) Metastatic Duct Carcinoma of Breast to 20 Axillary Lymph nodes and Aggregates Of Lymph Nodes with Fibrofatty Tissue Infiltration (5 mm. to 4 cm. in greatest diameter, B Right Mastectomy.



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